Balanites Aegyptiaca Fruits' Valorisation by Liquid Biofuels Production
Kosi Mawuéna Novidzro,
Balbine Amoussou Fagla,
Bidossessi Saturnin Houndji,
Mamatchi Melila,
Kokouvi Dotse,
Kossi Honoré Koumaglo
Issue:
Volume 7, Issue 4, July 2019
Pages:
102-112
Received:
24 September 2019
Accepted:
12 October 2019
Published:
23 October 2019
Abstract: Today, the fight against global warming is a major challenge for the whole world. The widespread use of biofuels is indeed one of the credible alternatives that can lead to a significant reduction in greenhouse gas (GHG) emissions. This study aims to promote the fruits of the desert date in bioenergy. The various treatments showed that the fruits are composed of 52.67 ± 0.18% of nuclei, 40.08 ± 0.50% of mesocarps and 7.26 ± 0.33% of epicarps and other solid particles. From the mesocarps, bioethanol was produced with a yield of 14.74 ± 0.06%; while by Soxhlet extraction of almonds with hexane gave a vegetable oil with a yield of 44.58 ± 5.69%. The monitoring of the ethanolic fermentation reaction, carried out with Saccharomyces cerevisiae yeasts revealed that a pH of 4.0 optimized the reaction, with an attenuation limit of 54.17%. GC-FID analysis showed that other reactions which should compete with ethanolic fermentation, were almost inhibited by the effectiveness of the kinetic control. GC-FID analysis of the chemical composition of the biodiesel produced with the crude oil has showed the presence of oleic acid (41.90%), linoleic acid (29.27%), palmitic acid (12.47%), β-linolenic (10.89%) and stearic (1.17%). Physicochemical analysis and the comparison of energy characteristics indicated that the biofuels produced in this study have properties similar to those of petrodiesel and some standard biofuels. Therefore, the fruits of Balanites aegyptiaca are an interesting source of liquid biofuels that can replace petrol and conventional diesel, the most used fossil fuels in transportation.
Abstract: Today, the fight against global warming is a major challenge for the whole world. The widespread use of biofuels is indeed one of the credible alternatives that can lead to a significant reduction in greenhouse gas (GHG) emissions. This study aims to promote the fruits of the desert date in bioenergy. The various treatments showed that the fruits a...
Show More
Study of Interaction Between Angiotensin-converting Enzyme ACE and Diuretic Inhibitor by Molecular Modeling
Mesli Fouzia,
Missoum Noureddine,
Ghalem Said
Issue:
Volume 7, Issue 4, July 2019
Pages:
113-119
Received:
18 September 2019
Accepted:
28 September 2019
Published:
28 October 2019
Abstract: Background: Molecular modeling methods are now used routinely to investigate the structure, dynamics, surface properties, and thermodynamics of inorganic, biological, and polymeric systems. Most current drugs target enzymes. This theoretical approach enables to predict the mode of interaction of a ligand with its receptor. The inhibition of Angiotensin-converting enzyme (ACE) is an important approach in the treatment of Heart failure (HF). The three families of Diuretic are used for inhibiting ACE. Our work is the study of molecular interaction between the enzyme (Angiotensin Converting) and the substrates (inihibitor for ACE). Various tools of molecular modeling are used to carry out this work (molecular mechanics, molecular dynamics and molecular docking) (MOE). The introduction of bulky groups causes a conformational rearrangement in thea ctive site pocket, which will probably be reinforced and thus complement its activity. The results obtained from this work, in which the inhibitions of Angiotensin Converting by molecular modeling methods have been demonstrated. In conclusion, taking into account the results obtained in this study, inhibition of Angiotensin Converting by molecular modeling methods has been elucidated, which allow us to conclude that Bumetanide (loopDiuretic) when water is included in the docking simulation has a better inhibition of Angiotensin Converting.
Abstract: Background: Molecular modeling methods are now used routinely to investigate the structure, dynamics, surface properties, and thermodynamics of inorganic, biological, and polymeric systems. Most current drugs target enzymes. This theoretical approach enables to predict the mode of interaction of a ligand with its receptor. The inhibition of Angiote...
Show More
